Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC7338795 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Liu Xiaoliu X Zhao Ming M Xu Zheng Z Xu Hong H Li Sha S
Frontiers in bioengineering and biotechnology 20200630
Welan gum is a widely used microbial polysaccharide produced by <i>Sphingomonas</i> sp. However, an important factor hindering the expansion of its production is the maladaptation of strain to fermentation conditions. In this work, the global transcriptional regulator gene <i>irre</i> was selected as a stress-resistant element. And it was integrated into the site of the genomic carotene synthesis key enzyme gene <i>crtB</i> to construct a robust carotenoid-free welan gum producing strain. Fermen ...[more]