Gene Set Analysis: Challenges, Opportunities, and Future Research.
Ontology highlight
ABSTRACT:
SUBMITTER: Maleki F
PROVIDER: S-EPMC7339292 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Gene Set Analysis: Challenges, Opportunities, and Future Research.
Maleki Farhad F Ovens Katie K Hogan Daniel J DJ Kusalik Anthony J AJ
Frontiers in genetics 20200630
Gene set analysis methods are widely used to provide insight into high-throughput gene expression data. There are many gene set analysis methods available. These methods rely on various assumptions and have different requirements, strengths and weaknesses. In this paper, we classify gene set analysis methods based on their components, describe the underlying requirements and assumptions for each class, and provide directions for future research in developing and evaluating gene set analysis meth ...[more]
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