Targeting dementias through cancer kinases inhibition.
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ABSTRACT:
SUBMITTER: Fagiani F
PROVIDER: S-EPMC7341824 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Targeting dementias through cancer kinases inhibition.
Fagiani Francesca F Lanni Cristina C Racchi Marco M Govoni Stefano S
Alzheimer's & dementia (New York, N. Y.) 20200708 1
The failures in Alzheimer's disease (AD) therapy strongly suggest the importance of reconsidering the research strategies analyzing other mechanisms that may take place in AD as well as, in general, in other neurodegenerative dementias. Taking into account that in AD a variety of defects result in neurotransmitter activity and signaling efficiency imbalance, neuronal cell degeneration and defects in damage/repair systems, aberrant and abortive cell cycle, glial dysfunction, and neuroinflammation ...[more]
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