Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity.
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ABSTRACT:
SUBMITTER: Nash RJ
PROVIDER: S-EPMC7346245 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
Iminosugar idoBR1 Isolated from Cucumber <i>Cucumis sativus</i> Reduces Inflammatory Activity.
Nash Robert J RJ Bartholomew Barbara B Penkova Yana B YB Rotondo Dino D Yamasaka Fernanda F Stafford Graham P GP Jenkinson Sarah F SF Fleet George W J GWJ
ACS omega 20200623 26
Cucumbers have been anecdotally claimed to have anti-inflammatory activity for a long time, but the active principle was not identified. idoBR1, (2<i>R</i>,3<i>R</i>,4<i>R</i>,5<i>S</i>)-3,4,5-trihydroxypiperidine-2-carboxylic acid, is an iminosugar amino acid isolated from fruits of certain cucumbers, <i>Cucumis sativus</i> (Cucurbitaceae). It has no chromophore and analytically behaves like an amino acid making detection and identification difficult. It has anti-inflammatory activity reducing ...[more]
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