Ontology highlight
ABSTRACT:
SUBMITTER: Schwartz HS
PROVIDER: S-EPMC7347156 | biostudies-literature | 2002 Mar
REPOSITORIES: biostudies-literature
Schwartz H S HS Eskew J D JD Butler M G MG
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20020301 2
Genetic studies including chromosome analysis, telomere reduction and telomere activity, DNA microsatellites and loss of heterozygosity (LOH) studies have been performed on giant cell tumor (GCT) of bone however whether this primary skeletal neoplasm represents a monoclonal or polyclonal proliferation is unknown. Utilizing a new assay to study the polymorphic human androgen receptor locus (HUMARA), the ratio of maternal inactive X-chromosome to the paternal inactive X (Lyon hypothesis) is determ ...[more]