Ontology highlight
ABSTRACT:
SUBMITTER: Lemelle L
PROVIDER: S-EPMC7347932 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Lemelle Laurence L Simionovici Alexandre A Colin Philippe P Knott Graham G Bohic Sylvain S Cloetens Peter P Schneider Bernard L BL
Communications biology 20200709 1
Sub-cellular trace element quantifications of nano-heterogeneities in brain tissues offer unprecedented ways to explore at elemental level the interplay between cellular compartments in neurodegenerative pathologies. We designed a quasi-correlative method for analytical nanoimaging of the substantia nigra, based on transmission electron microscopy and synchrotron X-ray fluorescence. It combines ultrastructural identifications of cellular compartments and trace element nanoimaging near detection ...[more]