Wnt Signaling in Gynecologic Malignancies.
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ABSTRACT:
SUBMITTER: McMellen A
PROVIDER: S-EPMC7348953 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Wnt Signaling in Gynecologic Malignancies.
McMellen Alexandra A Woodruff Elizabeth R ER Corr Bradley R BR Bitler Benjamin G BG Moroney Marisa R MR
International journal of molecular sciences 20200616 12
Gynecologic malignancies, including ovarian cancer, endometrial cancer, and cervical cancer, affect hundreds of thousands of women worldwide every year. Wnt signaling, specifically Wnt/β-catenin signaling, has been found to play an essential role in many oncogenic processes in gynecologic malignancies, including tumorigenesis, metastasis, recurrence, and chemotherapy resistance. As such, the Wnt/β-catenin signaling pathway has the potential to be a target for effective treatment, improving patie ...[more]
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