Ontology highlight
ABSTRACT:
SUBMITTER: Steffen T
PROVIDER: S-EPMC7349816 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Steffen Tara T Hassert Mariah M Hoft Stella G SG Stone E Taylor ET Zhang Jianfeng J Geerling Elizabeth E Grimberg Brian T BT Roberts M Scot MS Pinto Amelia K AK Brien James D JD
Vaccines 20200407 2
Zika virus (ZIKV) is a significant public health concern due to the pathogen's ability to be transmitted by either mosquito bite or sexual transmission, allowing spread to occur throughout the world. The potential consequences of ZIKV infection to human health, specifically neonates, necessitates the development of a safe and effective Zika virus vaccine. Here, we developed an intranasal Zika vaccine based upon the replication-deficient human adenovirus serotype 5 (hAd5) expressing ZIKV pre-memb ...[more]