Ontology highlight
ABSTRACT:
SUBMITTER: Kiseleva I
PROVIDER: S-EPMC7350028 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Kiseleva Irina I Isakova-Sivak Irina I Stukova Marina M Erofeeva Marianna M Donina Svetlana S Larionova Natalie N Krutikova Elena E Bazhenova Ekaterina E Stepanova Ekaterina E Vasilyev Kirill K Matyushenko Victoria V Krylova Marina M Galatonova Julia J Ershov Aleksey A Lioznov Dmitry D Sparrow Erin Grace EG Torelli Guido G Rudenko Larisa L
Vaccines 20200610 2
This study describes a double-blind randomized placebo-controlled phase I clinical trial in healthy adults of a new potential pandemic H7N9 live attenuated influenza vaccine (LAIV) based on the human influenza virus of Yangtze River Delta hemagglutinin lineage (ClinicalTrials.gov Identifier: NCT03739229). Two doses of H7N9 LAIV or placebo were administered intranasally to 30 and 10 subjects, respectively. The vaccine was well-tolerated and not associated with increased rates of adverse events or ...[more]