Mnemonic prediction errors bias hippocampal states.
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ABSTRACT:
SUBMITTER: Bein O
PROVIDER: S-EPMC7351776 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
Mnemonic prediction errors bias hippocampal states.
Bein Oded O Duncan Katherine K Davachi Lila L
Nature communications 20200710 1
When our experience violates our predictions, it is adaptive to upregulate encoding of novel information, while down-weighting retrieval of erroneous memory predictions to promote an updated representation of the world. We asked whether mnemonic prediction errors promote hippocampal encoding versus retrieval states, as marked by distinct network connectivity between hippocampal subfields. During fMRI scanning, participants were cued to internally retrieve well-learned complex room-images and wer ...[more]
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