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ABSTRACT: Purpose
In this study, we investigated the association between adherence to the Dutch Healthy Diet index 2015 (DHD15-index) and incidence of prediabetes (preT2D) and Type 2 Diabetes (T2D) in a representative sample for the general Dutch population.Methods
Two prospective cohort studies, The Hoorn and The New Hoorn Study, were used for data analyses. In total, data from 2951 participants without diabetes at baseline (mean age 56.5?±?7.5 years; 49.6% male) were harmonized. Baseline dietary intake was assessed with validated Food Frequency Questionnaires and adherence to the DHD15-index was calculated (range 0-130). PreT2D and T2D were classified according to the WHO criteria 2011. Poisson regression was used to estimate prevalence ratios between participant scores on the DHD15-index and preT2D and T2D, adjusted for follow-up duration, energy intake, socio-demographic, and lifestyle factors. Change in fasting plasma glucose levels (mmol/L) over follow-up was analysed using linear regression analyses, additionally adjusted for baseline value.Results
During a mean follow-up of 6.3?±?0.7 years, 837 participants developed preT2D and 321 participants developed T2D. The highest adherence to the DHD15-index was significantly associated with lower T2D incidence [model 3, PRT3vsT1: 0.70 (0.53; 0.92), ptrend?=?0.01]. The highest adherence to the DHD15-index pointed towards a lower incidence of preT2D [PRT3vsT1: 0.87 (0.74; 1.03), ptrend?=?0.11]. Higher adherence to the DHD15-index was not associated with change in fasting plasma glucose levels [?10point: -?0.012 (-?0.034; 0.009)mmol/L].Conclusion
The present study showed that the highest compared to the lowest adherence to the DHD15-index was associated with a lower T2D incidence, and pointed towards a lower incidence of preT2D. These results support the benefits of adhering to the guidelines in T2D prevention.
SUBMITTER: den Braver NR
PROVIDER: S-EPMC7351860 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
den Braver Nicolette R NR Rutters Femke F van der Spek Andrea L J Kortlever ALJK Ibi Dorina D Looman Moniek M Geelen Anouk A Elders Petra P van der Heijden Amber A AA Brug Johannes J Lakerveld Jeroen J Soedamah-Muthu Sabita S SS Beulens Joline W J JWJ
European journal of nutrition 20190724 5
<h4>Purpose</h4>In this study, we investigated the association between adherence to the Dutch Healthy Diet index 2015 (DHD15-index) and incidence of prediabetes (preT2D) and Type 2 Diabetes (T2D) in a representative sample for the general Dutch population.<h4>Methods</h4>Two prospective cohort studies, The Hoorn and The New Hoorn Study, were used for data analyses. In total, data from 2951 participants without diabetes at baseline (mean age 56.5 ± 7.5 years; 49.6% male) were harmonized. Baseline ...[more]