Ontology highlight
ABSTRACT:
SUBMITTER: Sawalha Y
PROVIDER: S-EPMC7351990 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
OncoTargets and therapy 20200706
Mantle cell lymphoma (MCL) is an uncommon B-cell non-Hodgkin lymphoma characterized by an aggressive clinical course in the majority of patients. Despite recent improvements in outcomes, MCL remains incurable and a major therapeutic challenge. BTK inhibitors are the preferred treatment option for patients with relapsed/refractory MCL, including those unfit for chemotherapy or those with chemoresistant disease. In addition to ibrutinib and acalabrutinib, the FDA recently approved zanubrutinib for ...[more]