Uterine fibroids may play a protecting role against endometrial carcinoma in Chinese women with gynecological diseases.
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ABSTRACT:
SUBMITTER: Qiao L
PROVIDER: S-EPMC7352044 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
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Uterine fibroids may play a protecting role against endometrial carcinoma in Chinese women with gynecological diseases.
Qiao Li L Xia Lili L Dong Yan Y Cheng Yajuan Y Cao Hongbao H
Bioscience reports 20200701 7
<h4>Background</h4>It has been reported that uterine fibroids (UFs) may increase the risk of endometrial carcinoma (EC) with the underlying mechanism largely unknown. Here, we explore whether UF could be an influential factor for EC.<h4>Methods</h4>We have collected and analyzed clinical data from 4537 Chinese patients to study the co-incidence of UF and EC. Then, a large-scale literature-based data mining was conducted to identify genes implicated as UF downstream regulating targets and EC upst ...[more]
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