Small Ones to Fight a Big Problem-Intervention of Cancer Metastasis by Small Molecules.

ABSTRACT: Metastasis represents the most lethal attribute of cancer and critically limits successful therapies in many tumor entities. The clinical need is defined by the fact that all cancer patients, who have or who will develop distant metastasis, will experience shorter survival. Thus, the ultimate goal in cancer therapy is the restriction of solid cancer metastasis by novel molecularly targeted small molecule based therapies. Biomarkers identifying cancer patients at high risk for metastasis and simultaneously acting as key drivers for metastasis are extremely desired. Clinical interventions targeting these key molecules will result in high efficiency in metastasis intervention. In result of this, personalized tailored interventions for restriction and prevention of cancer progression and metas

SUBMITTER: Kobelt D 

PROVIDER: S-EPMC7352875 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature