Ontology highlight
ABSTRACT:
SUBMITTER: Hansson E
PROVIDER: S-EPMC7352879 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Hansson Erik E Glaser Jason J Jakobsson Kristina K Weiss Ilana I Wesseling Catarina C Lucas Rebekah A I RAI Wei Jason Lee Kai JLK Ekström Ulf U Wijkström Julia J Bodin Theo T Johnson Richard J RJ Wegman David H DH
Nutrients 20200602 6
<h4>Background</h4>Chronic kidney disease of non-traditional origin (CKDnt) is common among Mesoamerican sugarcane workers. Recurrent heat stress and dehydration is a leading hypothesis. Evidence indicate a key role of inflammation.<h4>Methods</h4>Starting in sports and heat pathophysiology literature, we develop a theoretical framework of how strenuous work in heat could induce kidney inflammation. We describe the release of pro-inflammatory substances from a leaky gut and/or injured muscle, al ...[more]