Ontology highlight
ABSTRACT:
SUBMITTER: Insuasty-Cepeda DS
PROVIDER: S-EPMC7352952 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Insuasty-Cepeda Diego Sebastián DS Barragán-Cárdenas Andrea Carolina AC Ochoa-Zarzosa Alejandra A López-Meza Joel E JE Fierro-Medina Ricardo R García-Castañeda Javier Eduardo JE Rivera-Monroy Zuly Jenny ZJ
International journal of molecular sciences 20200626 12
The effect on the cytotoxicity against breast cancer cell lines of the substitution of <sup>26</sup>Met residue in the sequence of the Bovine Lactoferricin-derived dimeric peptide LfcinB (20-30)<sub>2</sub>: (<sup>20</sup>RRWQWRMKKLG<sup>30</sup>)<sub>2</sub>-K-<i>Ahx</i> with amino acids of different polarity was evaluated. The process of the synthesis of the LfcinB (20-30)<sub>2</sub> analog peptides was similar to the original peptide. The cytotoxic assays showed that some analog peptides exh ...[more]