Ontology highlight
ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC7353919 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Wang Xin X He Siyu S Li Jian J Wang Jun J Wang Chengyi C Wang Mingwei M He Danni D Lv Xingfeng X Zhong Qiuyan Q Wang Hongjiu H Wang Zhenzhen Z
PeerJ 20200708
The life cycle of intracellular RNA mainly involves transcriptional production, splicing maturation and degradation processes. Their dynamic changes are termed as RNA life cycle dynamics (RLCD). It is still challenging for the accurate and robust identification of RLCD under unknow the functional form of RLCD. By using the pulse model, we developed an R package named pulseTD to identify RLCD by integrating 4sU-seq and RNA-seq data, and it provides flexible functions to capture continuous changes ...[more]