Ontology highlight
ABSTRACT:
SUBMITTER: Yoo H
PROVIDER: S-EPMC7356503 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Yoo Hongseok H Lee Jin Young JY Park Junseon J Yang Jeong Hoon JH Suh Gee Young GY Jeon Kyeongman K
Journal of clinical medicine 20200601 6
Recent studies have suggested that TNF-related apoptosis-inducing ligand (TRAIL) is associated with mortality in sepsis, possibly through necroptosis. The objective of this study was to analyze the association between the plasma level of TRAIL and sepsis severity and outcomes. Furthermore, the plasma level of TRAIL was compared to that of receptor-interacting protein kinase-3 (RIPK3), a key executor of necroptosis, to identify any correlation between TRAIL and necroptosis. Plasma levels of TRAIL ...[more]