Ontology highlight
ABSTRACT:
SUBMITTER: Mullooly M
PROVIDER: S-EPMC7357278 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Mullooly Maeve M Puvanesarajah Samantha S Fan Shaoqi S Pfeiffer Ruth M RM Olsson Linnea T LT Hada Manila M Kirk Erin L EL Vacek Pamela M PM Weaver Donald L DL Shepherd John J Mahmoudzadeh Amir A Wang Jeff J Malkov Serghei S Johnson Jason M JM Hewitt Stephen M SM Herschorn Sally D SD Sherman Mark E ME Troester Melissa A MA Gierach Gretchen L GL
Cancer prevention research (Philadelphia, Pa.) 20191023 12
Delayed terminal duct lobular unit (TDLU) involution is associated with elevated mammographic breast density (MD). Both are independent breast cancer risk factors among women with benign breast disease (BBD). Prior digital analyses of normal breast tissues revealed that epithelial nuclear density (END) and TDLU involution are inversely correlated. Accordingly, we examined associations of END, TDLU involution, and MD in BBD clinical biopsies. This study included digitized images of 262 representa ...[more]