Ontology highlight
ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC7358039 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Chen Wu W Sinha Bharati B Li Yi Y Benowitz Larry L Chen Qinhua Q Zhang Zhenghong Z Patel Nirav J NJ Aziz-Sultan Ali M AM Chiocca Antonio E AE Wang Xin X
Molecular neurobiology 20180608 2
Ischemic stroke (IS) is a leading disease with high mortality and disability, as well as with limited therapeutic window. Biomarkers for earlier diagnosis of IS have long been pursued. Family and twin studies confirm that genetic variations play an important role in IS pathogenesis. Besides DNA mutations found previously by genetic linkage analysis for monogenic IS (Mendelian inheritance), recent studies using genome-wide associated study (GWAS) and microRNA expression profiling have resulted in ...[more]