Ontology highlight
ABSTRACT:
SUBMITTER: Gambichler T
PROVIDER: S-EPMC7358098 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Gambichler Thilo T Reuther Judith J Scheel Christina H CH Becker Jürgen Christian JC
Journal for immunotherapy of cancer 20200701 2
The present review summarizes up-to-date evidence addressing the frequently discussed clinical controversies regarding the use of immune checkpoint inhibitors (ICIs) in cancer patients with viral infections, including AIDS, hepatitis B and C, progressive multifocal leukoencephalopathy, influenza, and COVID-19. In detail, we provide available information on (1) safety regarding the risk of new infections, (2) effects on the outcome of pre-existing infections, (3) whether immunosuppressive drugs u ...[more]