Ontology highlight
ABSTRACT:
SUBMITTER: Rea J
PROVIDER: S-EPMC7359305 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Rea Jessica J Menci Valentina V Tollis Paolo P Santini Tiziana T Armaos Alexandros A Garone Maria Giovanna MG Iberite Federica F Cipriano Andrea A Tartaglia Gian Gaetano GG Rosa Alessandro A Ballarino Monica M Laneve Pietro P Caffarelli Elisa E
Cell death & disease 20200713 7
Neuronal differentiation is a timely and spatially regulated process, relying on precisely orchestrated gene expression control. The sequential activation/repression of genes driving cell fate specification is achieved by complex regulatory networks, where transcription factors and noncoding RNAs work in a coordinated manner. Herein, we identify the long noncoding RNA HOTAIRM1 (HOXA Transcript Antisense RNA, Myeloid-Specific 1) as a new player in neuronal differentiation. We demonstrate that the ...[more]