Unknown

Dataset Information

0

The prognostic value of six survival-related genes in bladder cancer.


ABSTRACT: This study was conducted to identify genes that are differentially expressed in paracancerous tissue and to determine the potential predictive value of selected gene panel. Gene transcriptome data of bladder tissue was downloaded from UCSC Xena browser and NCBI GEO repository, including GTEx (the Genotype-Tissue Expression project) data, TCGA (The Cancer Genome Atlas) data, and GEO (Gene Expression Omnibus) data. Differentially Expressed Genes (DEGs) analysis was performed to identify tumor-DEGs candidate genes, using the intersection of tumor-paracancerous DEGs genes and paracancerous-normal DEGs genes. The survival-related genes were screened by Kaplan-Meier (KM) survival analysis and univariable Cox regression with the cutoff criteria of KM?

SUBMITTER: Cheng S 

PROVIDER: S-EPMC7359373 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

altmetric image

Publications

The prognostic value of six survival-related genes in bladder cancer.

Cheng Shuting S   Jiang Zhou Z   Xiao Jing J   Guo Huiling H   Wang Zhengrong Z   Wang Yuhui Y  

Cell death discovery 20200713


This study was conducted to identify genes that are differentially expressed in paracancerous tissue and to determine the potential predictive value of selected gene panel. Gene transcriptome data of bladder tissue was downloaded from UCSC Xena browser and NCBI GEO repository, including GTEx (the Genotype-Tissue Expression project) data, TCGA (The Cancer Genome Atlas) data, and GEO (Gene Expression Omnibus) data. Differentially Expressed Genes (DEGs) analysis was performed to identify tumor-DEGs  ...[more]

Similar Datasets

| S-EPMC8635965 | biostudies-literature
| S-EPMC7399341 | biostudies-literature
| S-EPMC6729005 | biostudies-literature
| S-EPMC7733340 | biostudies-literature
| S-EPMC7661532 | biostudies-literature
| S-EPMC7482003 | biostudies-literature
| S-EPMC7837905 | biostudies-literature
| S-EPMC6951294 | biostudies-literature
| S-EPMC8145616 | biostudies-literature
| S-EPMC6684930 | biostudies-literature