Ontology highlight
ABSTRACT:
SUBMITTER: Huang HY
PROVIDER: S-EPMC7359586 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Huang Hui-Ying HY Liang Xue-Yan XY Lin Li-Yun LY Chen Jiang-Tao JT Ehapo Carlos Salas CS Eyi Urbano Monsuy UM Li Jian J Jiang Ting-Ting TT Zheng Yu-Zhong YZ Zha Guang-Cai GC Xie Dong-De DD He Jin-Quan JQ Chen Wei-Zhong WZ Liu Xiang-Zhi XZ Mo Huan-Tong HT Chen Xin-Yao XY Lin Min M
Malaria journal 20200713 1
<h4>Background</h4>Plasmodium falciparum circumsporozoite protein (PfCSP) is a potential malaria vaccine candidate, but various polymorphisms of the pfcsp gene among global P. falciparum population become the major barrier to the effectiveness of vaccines. This study aimed to investigate the genetic polymorphisms and natural selection of pfcsp in Bioko and the comparison among global P. falciparum population.<h4>Methods</h4>From January 2011 to December 2018, 148 blood samples were collected fro ...[more]