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Continuous Renal Replacement Therapy for a Patient with Severe COVID-19.


ABSTRACT: The outbreak of coronavirus disease 2019 (COVID-19) is a global health threat. It is a respiratory disease, and acute kidney injury (AKI) is rare; however, if a patient develops severe AKI, renal replacement therapy (RRT) should be considered. Recently, we had a critically ill COVID-19 patient who developed severe AKI and needed continuous RRT (CRRT). To avoid the potential risk of infection from CRRT effluents, we measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic material in the effluents by qRT-PCR, and low copy numbers of the viral genome were detected. Due to unstable hemodynamic status in critically ill patients, CRRT should be the first choice for severe AKI in COVID-19 patients. We suggest prevention of clinical infection and control during administration of RRT in the acute phase of COVID-19 patients with AKI or multiple organ failure.

SUBMITTER: Katagiri D 

PROVIDER: S-EPMC7360495 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Continuous Renal Replacement Therapy for a Patient with Severe COVID-19.

Katagiri Daisuke D   Ishikane Masahiro M   Ogawa Tatsunori T   Kinoshita Noriko N   Katano Harutaka H   Suzuki Tadaki T   Fukaya Takashi T   Hinoshita Fumihiko F   Ohmagari Norio N  

Blood purification 20200611 1


The outbreak of coronavirus disease 2019 (COVID-19) is a global health threat. It is a respiratory disease, and acute kidney injury (AKI) is rare; however, if a patient develops severe AKI, renal replacement therapy (RRT) should be considered. Recently, we had a critically ill COVID-19 patient who developed severe AKI and needed continuous RRT (CRRT). To avoid the potential risk of infection from CRRT effluents, we measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic mat  ...[more]

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