Ontology highlight
ABSTRACT:
SUBMITTER: Hamarsheh S
PROVIDER: S-EPMC7360837 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in immunology 20200708
Inflammation is involved in tumor development and progression as well as antitumor response to therapy. In the past decade, the crosstalk between inflammation, immunity, and cancer has been investigated extensively, which led to the identification of several underlying mechanisms and cells involved. The formation of inflammasome complexes leads to the activation of caspase-1, production of interleukin (IL)-1β, and IL-18 and pyroptosis. Multiple studies have shown the involvement of NLRP3 inflamm ...[more]