Ontology highlight
ABSTRACT:
SUBMITTER: Haldar K
PROVIDER: S-EPMC7362436 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Haldar Koirobi K George Leena L Wang Zhang Z Mistry Vijay V Ramsheh Mohammadali Yavari MY Free Robert C RC John Catherine C Reeve Nicola F NF Miller Bruce E BE Tal-Singer Ruth R Webb Adam J AJ Brookes Anthony J AJ Tobin Martin D MD Singh Dave D Donaldson Gavin C GC Wedzicha Jadwiga A JA Brown James R JR Barer Michael R MR Brightling Christopher E CE
Respiratory research 20200714 1
<h4>Background</h4>Airway bacterial dysbiosis is a feature of chronic obstructive pulmonary disease (COPD). However, there is limited comparative data of the lung microbiome between healthy smokers, non-smokers and COPD.<h4>Methods</h4>We compared the 16S rRNA gene-based sputum microbiome generated from pair-ended Illumina sequencing of 124 healthy subjects (28 smokers and 96 non-smokers with normal lung function), with single stable samples from 218 COPD subjects collected from three UK clinica ...[more]