The vaginal microbiota and its association with human papillomavirus, Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections: a systematic review and meta-analysis.

ABSTRACT: BACKGROUND:The vaginal microbiota may modulate susceptibility to human papillomavirus (HPV), Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections. Persistent infection with a carcinogenic HPV is a prerequisite for cervical cancer, and C. trachomatis, N. gonorrheae and M. genitalium genital infections are all associated with pelvic inflammatory disease and subsequent infertility issues. OBJECTIVES:To evaluate the association between these infections and the vaginal microbiota. DATA SOURCES:The search was conducted on Medline and the Web of Science for articles published between 2000 and 2016. STUDY ELIGIBILITY CRITERIA:Inclusion criteria included a measure of association for vaginal microbiota and one of the considered STIs, female population, cohort, cross-sect

SUBMITTER: Tamarelle J 

PROVIDER: S-EPMC7362580 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature