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Molar-Incisor Hypomineralisation and Allergic March.

ABSTRACT: Background:Molar-incisor hypomineralisation is a disturbance in dental development that involves first permanent molars as well as permanent incisors with a prevalence that ranges from 2.5% to 40%. Aim:The objective of this study was to investigate the effect of atopic diseases on the development of molar-incisor hypomineralisation. Material and methods:The study was based on the review of the medical records of a group of 102 children whose age was between eight and 12 years and 11 months and who had previously been diagnosed with MIH. Results:An association (?2, p?0.05) has been found between molar-incisor hypomineralisation in children's mouths and the existence of: atopic dermatitis (OR=2.504; 1.54-4.05 CI 95%), food allergies (OR=2.171; 1.03-4.56 CI 95%), allergic rhinitis (OR=0.17; 0.02-1.27 CI 95%), and asthmatic bronchitis/asthma (OR=1.707; 1.05-2.76 CI 95%). When analyzing the pathologies by location, we found that atopic dermatitis, food allergies, allergic rhinitis and asthma were more frequent in children who had (p?0.05) #12, #11, #21, #22, #36, #31, #41 and #42 affected. Conclusions:The association between molar-incisor hypomineralisation and the presence of atopic diseases in the first 36 months of life underlines the convenience of approaching this problem from a multidisciplinary perspective.

SUBMITTER: Hernandez M

PROVIDER: S-EPMC7362738 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Molar-Incisor Hypomineralisation and Allergic March.

Hernandez Miguel M Mendioroz Jacobo J

Acta stomatologica Croatica 20200601 2

<h4>Background</h4>Molar-incisor hypomineralisation is a disturbance in dental development that involves first permanent molars as well as permanent incisors with a prevalence that ranges from 2.5% to 40%.<h4>Aim</h4>The objective of this study was to investigate the effect of atopic diseases on the development of molar-incisor hypomineralisation.<h4>Material and methods</h4>The study was based on the review of the medical records of a group of 102 children whose age was between eight and 12 yea ...[more]

PMID: 32801371

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Project description:ObjectivesOutcome and comparator choice strongly determine the validity and implementation of clinical trial results. We aimed to assess outcome and comparator choice in intervention studies on molar incisor hypomineralisation (MIH) using systematic review and social network analysis (SNA).Design and data sourcesMedline, Embase, Cochrane Central, Google Scholar, opengrey.eu as well as DRKS.de and Clinicaltrials.gov were searched for MIH intervention studies. The search covered the period from 1980 to 2019.Eligibility criteriaClinical single-arm/multiarm, controlled/uncontrolled studies reporting on the management of MIH were included. Reported outcomes and comparators were extracted and categorised. SNA was used to evaluate comparator choice and the resulting trial networks.Data extractionOf the 7979 identified records, 100 were evaluated in full text and 35 studies (17 randomised controlled trials, 14 prospective and 4 retrospective cohort studies) were included.ResultsIn total, 2124 patients with a mean age of 11 years (min/max 6/70 years) were included. Outcomes fell in one of 11 different outcome categories: restoration success, aesthetic improvement, pain/hypersensitivity/discomfort, mineral gain, space management, anaesthesia effectiveness, preventive success, efficiency, quality of life, gingival and periodontal health and patient satisfaction. Comparators were mainly restorative interventions (17 studies), remineralisation (3), treatment of hypersensitivity (10), aesthetic interventions (5) and orthodontic interventions (3). Two highly clustered comparator networks emerged; many interventions were not robustly linked to these networks.ConclusionsMIH intervention studies recorded both clinically centred and patient-centred outcomes. Core outcome set development should consider these and supplement them with outcomes on, for example, applicability. The high number of compared interventions tested in only few studies and our SNA results implicate that the current evidence may not be robust.

Dataset Information

Molar-Incisor Hypomineralisation and Allergic March.

Publications

Molar-Incisor Hypomineralisation and Allergic March.

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