Pseudomonas aeruginosa mexT is an indicator of PAO1 strain integrity.
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ABSTRACT:
SUBMITTER: LoVullo ED
PROVIDER: S-EPMC7363278 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
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<i>Pseudomonas aeruginosa mexT</i> is an indicator of PAO1 strain integrity.
LoVullo Eric D ED Schweizer Herbert P HP
Journal of medical microbiology 20191218 1
Laboratory research with <i>Pseudomonas aeruginosa</i> commonly involves the prototype strain PAO1. There is continued concern that PAO1 sublines maintained and propagated in the same laboratory or different laboratories exhibit genetic and phenotypic variability that may affect the reproducibility and validity of research. Whole-genome sequencing and other research identified the <i>mexT</i> locus as a mutational hotspot, but the explication of the diverse mutations present in the various subli ...[more]
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