Prenatal exposure to ambient air multi-pollutants significantly impairs intrauterine fetal development trajectory.

ABSTRACT:

Background

Impaired in utero fetal growth trajectory may have long term health consequences of the newborns and increase risk of adulthood metabolic diseases. Prenatal exposure to air pollution has been linked to fetal development restriction; however, the impact of exposure to ambient air pollutants on the entire course of intrauterine fetal development has not been comprehensively investigated.

Methods

During 2015-2018, two cohorts of mother-infant dyads (N = 678 and 227) were recruited in Shanghai China, from which three categories of data were systematically collected: (1) daily exposure to six air pollutants during pregnancy, (2) fetal biometry in the 2nd (gestational week 24, [GW24]) and 3rd trimester (GW36), and (3) neonatal outcomes at birth. We investigated the impa

SUBMITTER: Shao X 

PROVIDER: S-EPMC7363555 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature