Ontology highlight
ABSTRACT:
SUBMITTER: Zaaber I
PROVIDER: S-EPMC7364016 | biostudies-literature | 2020 Jan-Mar
REPOSITORIES: biostudies-literature
Zaaber I I Mestiri S S Marmouch H H Bel Hadj Jrad Tensaout B B
Acta endocrinologica (Bucharest, Romania : 2005) 20200101 1
<h4>Background</h4>Autoimmune thyroid diseases (AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT) are complex genetic diseases. TSHR is considered as candidate gene in GD. This finding prompted us to investigate the association of TSHR gene polymorphism with the risk and the prognosis of AITD in Tunisia.<h4>Methods</h4>A total of 84 healthy controls and 91 patients with AITD (69HT and 22 GD) were genotyped for TSHR rs74067403A>G polymorphism and 134 healthy controls and 149 p ...[more]