Project description:Interventions: A group:Intervention: The PEEP incremental method for lung recruitment starts with PEEP 5 cmH2O, increasing PEEP 5 cmH2O every 5 breaths until PEEP reaches 20cmH2O and maintaining breathing 10 times. Then decrease PEEP to 5 cmH2O by the reversed operation. After lung recruitment, PEEP titration was performed. PEEP gradually decreased from 20 cmH2O to 4 cmH2O, and decreased by 2 cmH2O every 5 breaths. The PEEP value corresponding to the lowest driving pressure was the optimal PEEP value. The method of lung recruitment is the same as before every 1 hour in the future.;Bgroup:Intervention: The PEEP incremental method of lung recruitment starts with PEEP 5 cmH2O and increases PEEP 5cmH2O every 5 breaths until PEEP reaches 20 cmH2O and maintains breathing for 10 times. Then reverse the operation to decrease PEEP to 5 cmH2O. After lung recruitment, PEEP titration was performed. PEEP gradually decreased from 20 cmH2O to 4 cmH2O, and decreased by 2cmH2O every 5 breaths. The PEEP value corresponding to the lowest driving pressure was the optimal PEEP value. No lung recruitment in the future.;C group:Constant 5cmH2O PEEP Primary outcome(s): global impedance curve amplitude Study Design: Parallel

| 113337 | ecrin-mdr-crc

Positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome: the heterogeneous effects.

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| S-EPMC8674862 | biostudies-literature

Influence of overdistension/recruitment induced by high positive end-expiratory pressure on ventilation-perfusion matching assessed by electrical impedance tomography with saline bolus.

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| S-EPMC7523261 | biostudies-literature

Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration.

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| S-EPMC3177558 | biostudies-literature

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Project description: Not available