Ontology highlight
ABSTRACT:
SUBMITTER: Tardelli M
PROVIDER: S-EPMC7366061 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
World journal of gastroenterology 20200701 25
Dietary oversupply of triglycerides represent the hallmark of obesity and connected complications in the liver such as non-alcoholic fatty liver disease and non-alcoholic steatohepatitis, which eventually progress to cirrhosis and hepatocellular carcinoma. Monoacylglycerol lipase is the last enzymatic step in the hydrolysis of triglycerides, generating glycerol and fatty acids (FAs), which are signaling precursors in physiology and disease. Notably, monoacylglycerol lipase (MGL) also hydrolyzes ...[more]