RPmirDIP: Reciprocal Perspective improves miRNA targeting prediction.
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ABSTRACT:
SUBMITTER: Kyrollos DG
PROVIDER: S-EPMC7366700 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
RPmirDIP: Reciprocal Perspective improves miRNA targeting prediction.
Kyrollos Daniel G DG Reid Bradley B Dick Kevin K Green James R JR
Scientific reports 20200716 1
MicroRNAs (miRNAs) are short, non-coding RNAs that interact with messenger RNA (mRNA) to accomplish critical cellular activities such as the regulation of gene expression. Several machine learning methods have been developed to improve classification accuracy and reduce validation costs by predicting which miRNA will target which gene. Application of these predictors to large numbers of unique miRNA-gene pairs has resulted in datasets comprising tens of millions of scored interactions; the large ...[more]
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