Ontology highlight
ABSTRACT:
SUBMITTER: Raina R
PROVIDER: S-EPMC7366888 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Nature reviews. Nephrology 20200408 8
Hyperammonaemia in children can lead to grave consequences in the form of cerebral oedema, severe neurological impairment and even death. In infants and children, common causes of hyperammonaemia include urea cycle disorders or organic acidaemias. Few studies have assessed the role of extracorporeal therapies in the management of hyperammonaemia in neonates and children. Moreover, consensus guidelines are lacking for the use of non-kidney replacement therapy (NKRT) and kidney replacement therapi ...[more]