Ontology highlight
ABSTRACT:
SUBMITTER: Fabian P
PROVIDER: S-EPMC7370054 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Fabian Piotr P Banach Mateusz M Stapor Katarzyna K Konieczny Leszek L Ptak-Kaczor Magdalena M Roterman Irena I
International journal of molecular sciences 20200630 13
The issue of changing the structure of globular proteins into an amyloid form is in the focus of researchers' attention. Numerous experimental studies are carried out, and mathematical models to define the essence of amyloid transformation are sought. The present work focuses on the issue of the hydrophobic core structure in amyloids. The form of ordering the hydrophobic core in globular proteins is described by a 3D Gaussian distribution analog to the distribution of hydrophobicity in a spheric ...[more]