Ontology highlight
ABSTRACT:
SUBMITTER: Godfrey AK
PROVIDER: S-EPMC7370882 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Genome research 20200527 6
Little is known about how human Y-Chromosome gene expression directly contributes to differences between XX (female) and XY (male) individuals in nonreproductive tissues. Here, we analyzed quantitative profiles of Y-Chromosome gene expression across 36 human tissues from hundreds of individuals. Although it is often said that Y-Chromosome genes are lowly expressed outside the testis, we report many instances of elevated Y-Chromosome gene expression in a nonreproductive tissue. A notable example ...[more]