Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma.
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ABSTRACT:
SUBMITTER: Han W
PROVIDER: S-EPMC7371605 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma.
Han Wei W Shi Jia J Cao Jiachao J Dong Bo B Guan Wei W
OncoTargets and therapy 20200716
Glioma is the most common type of intracranial malignant tumor, with a great recurrence rate due to its infiltrative growth, treatment resistance, intra- and intertumoral genetic heterogeneity. Recently, accumulating studies have illustrated that activated aerobic glycolysis participated in various cellular and clinical activities of glioma, thus influencing the efficacy of radiotherapy and chemotherapy. However, the glycolytic process is too complicated and ambiguous to serve as a novel therapy ...[more]
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