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Enhanced recovery after surgery on multiple clinical outcomes: Umbrella review of systematic reviews and meta-analyses.


ABSTRACT:

Background

Previously, many meta-analyses have reported the impact of enhanced recovery after surgery (ERAS) programs on many surgical specialties.

Objectives

To systematically assess the effects of ERAS pathways on multiple clinical outcomes in surgery.

Design

An umbrella review of meta-analyses.

Date sources

PubMed, Embase, Web of Science and the Cochrane Library.

Results

The umbrella review identified 23 meta-analyses of interventional study and observational study. Consistent and robust evidence shown that the ERAS programs can significantly reduce the length of hospital stay (MD: -2.349 days; 95%CI: -2.740 to -1.958) and costs (MD: -$639.064; 95%CI:: -933.850 to -344.278) in all the surgery patients included in the review compared with traditional perioperative care. The ERAS programs would not increase mortality in all surgeries and can even reduce 30-days mortality rate (OR: 0.40; 95%CI: 0.23 to 0.67) in orthopedic surgery. Meanwhile, it also would not increase morbidity except laparoscopic gastric cancer surgery (RR: 1.49; 95%CI: 1.04 to 2.13). Moreover, readmission rate was increased in open gastric cancer surgery (RR: 1.92; 95%CI: 1.00 to 3.67).

Conclusion

The ERAS programs are considered to be safe and efficient in surgery patients. However, precaution is necessary for gastric cancer surgery.

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7373593 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Publications

Enhanced recovery after surgery on multiple clinical outcomes: Umbrella review of systematic reviews and meta-analyses.

Zhang Xingxia X   Yang Jie J   Chen Xinrong X   Du Liang L   Li Ka K   Zhou Yong Y  

Medicine 20200701 29


<h4>Background</h4>Previously, many meta-analyses have reported the impact of enhanced recovery after surgery (ERAS) programs on many surgical specialties.<h4>Objectives</h4>To systematically assess the effects of ERAS pathways on multiple clinical outcomes in surgery.<h4>Design</h4>An umbrella review of meta-analyses.<h4>Date sources</h4>PubMed, Embase, Web of Science and the Cochrane Library.<h4>Results</h4>The umbrella review identified 23 meta-analyses of interventional study and observation  ...[more]

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