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Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors.

ABSTRACT: Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof.

SUBMITTER: Neumann B

PROVIDER: S-EPMC7374321 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Electrochemical Biosensors Employing Natural and Artificial Heme Peroxidases on Semiconductors.

Neumann Bettina B Wollenberger Ulla U

Sensors (Basel, Switzerland) 20200701 13

Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focus ...[more]

PMID: 32630267

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