Ontology highlight
ABSTRACT:
SUBMITTER: Umesawa Y
PROVIDER: S-EPMC7374467 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Journal of autism and developmental disorders 20200801 8
Several motor disabilities accompanied with autism spectrum disorder (ASD) are widely known despite limited reports of underlying neural mechanisms. Gamma-aminobutyric acid (GABA) levels in the motor-related cortical areas modulate several motor performances in healthy participants. We hypothesized that abnormal GABA concentrations in the primary motor area (M1) and supplementary motor area (SMA) associate with different motor difficulties for ASD adolescents/adults. We found that increased GABA ...[more]