Ontology highlight
ABSTRACT:
SUBMITTER: Chen YG
PROVIDER: S-EPMC7374577 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Chen Yi-Guang YG Ciecko Ashley E AE Khaja Shamim S Grzybowski Michael M Geurts Aron M AM Lieberman Scott M SM
Scientific reports 20200721 1
Recent advances in genetic analyses have significantly refined human type 1 diabetes (T1D) associated loci. The goal of such effort is to identify the causal genes and have a complete understanding of the molecular pathways that independently or interactively influence cellular processes leading to the destruction of insulin producing pancreatic β cells. UBASH3A has been suggested as the underlying gene for a human T1D associated region on chromosome 21. To further evaluate the role of UBASH3A i ...[more]