Gene Mapping by RNA-sequencing: A Direct Way to Characterize Genes and Gene Expression through Targeted Queries of Large Public Databases.

ABSTRACT: Recent advances in genomics present new opportunities for enhancing knowledge about gene regulation and function across a wide spectrum of organisms and species. Understanding and evaluating this information at the individual gene level is challenging, and not only requires extracting, collating and interpreting data from public genetic repositories, but also recognizing that much of the information has been developed through implementation of computationally based exon-calling algorithms, and thus may be inaccurate. Moreover, as these data usually have not been validated experimentally, results also may be incomplete and incorrect. This has created a quality-control problem for scientists who want to use individual gene-specific information in their research. Here, I describe a simple exp

SUBMITTER: Rotwein P 

PROVIDER: S-EPMC7375414 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature