Ontology highlight
ABSTRACT:
SUBMITTER: Staudt N
PROVIDER: S-EPMC7375831 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Staudt Nicole N Giger Florence A FA Fielding Triona T Hutt James A JA Foucher Isabelle I Snowden Vicky V Hellich Agathe A Kiecker Clemens C Houart Corinne C
Development (Cambridge, England) 20191121 22
The embryonic development of the pineal organ, a neuroendocrine gland on top of the diencephalon, remains enigmatic. Classic fate-mapping studies suggested that pineal progenitors originate from the lateral border of the anterior neural plate. We show here, using gene expression and fate mapping/lineage tracing in zebrafish, that pineal progenitors originate, at least in part, from the non-neural ectoderm. Gene expression in chick indicates that this non-neural origin of pineal progenitors is co ...[more]