Ontology highlight
ABSTRACT:
SUBMITTER: Wei Y
PROVIDER: S-EPMC7376689 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Wei Yan Y Xu Hao H Xu Shuangmeng S Su Hui H Zhang Lichuang L Sun Ruize R Huang Di D Zhao Liqin L Wang Kaiqun K Hu Yinchun Y Lian Xiaojie X
ACS omega 20200710 28
Herein, we proposed a drug-free strategy named cell surface shellization to inhibit the motility of SKOV-3 and HeLa cells. We alternately deposited two- or three-layer cationic polyelectrolyte (PE) and anionic PE films on the surface of SKOV-3 and HeLa cells. Then, a mineral shell (calcium carbonate, CaCO<sub>3</sub>) was formed on the surface of polymer shells via electrostatic force and biomineralization. The CCK-8 assay results and live/dead staining showed that the surface shells strongly ag ...[more]