Ontology highlight
ABSTRACT:
SUBMITTER: Sharabiany S
PROVIDER: S-EPMC7376711 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Sharabiany Sarah S Blok Robin D RD Lapid Oren O Hompes Roel R Bemelman Wilhelmus A WA Alberts Victor P VP Lamme Bas B Wijsman Jan H JH Tuynman Jurriaan B JB Aalbers Arend G J AGJ Beets Geerard L GL Fabry Hans F J HFJ Cherepanin Ivan M IM Polat Fatih F Burger Jacobus W A JWA Rutten Harm J T HJT Bosker Robert J I RJI Talsma Koen K Rothbarth Joost J Verhoef Cees C van de Ven Anthony W H AWH van der Bilt Jarmila D W JDW de Graaf Eelco J R EJR Doornebosch Pascal G PG Leijtens Jeroen W A JWA Heemskerk Jeroen J Singh Baljit B Chaudhri Sanjay S Gerhards Michael F MF Karsten Tom M TM de Wilt Johannes H W JHW Bremers Andre J A AJA Vuylsteke Ronald J C L M RJCLM Heuff Gijsbert G van Geloven Anna A W AAW Tanis Pieter J PJ Musters Gijsbert D GD
BMC surgery 20200723 1
<h4>Background</h4>Abdominoperineal resection (APR) for rectal cancer is associated with high morbidity of the perineal wound, and controversy exists about the optimal closure technique. Primary perineal wound closure is still the standard of care in the Netherlands. Biological mesh closure did not improve wound healing in our previous randomised controlled trial (BIOPEX-study). It is suggested, based on meta-analysis of cohort studies, that filling of the perineal defect with well-vascularised ...[more]