Ontology highlight
ABSTRACT:
SUBMITTER: Lin H
PROVIDER: S-EPMC7377859 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Lin Huyu H You Bin B Lin Xiandong X Wang Xiaohu X Zhou Dongsheng D Chen Zhiqun Z Chen Yuanxiang Y Wang Ren R
Aging 20200706 13
Long non-coding RNAs (lncRNAs) have been largely reported to contribute to the development and progression of abdominal aortic aneurysm (AAA), a common vascular degenerative disease. The present study was set out with the aim to investigate the possible role of lncRNA Sox2ot in the development of AAA. In this study, we found that lncRNA Sox2ot and early growth response factor-1 (Egr1) were highly expressed, while microRNA (miR)-145 was poorly expressed in Ang II-induced AAA mice and oxidative st ...[more]