Ontology highlight
ABSTRACT:
SUBMITTER: Vinks AA
PROVIDER: S-EPMC7378965 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Vinks Alexander A AA Punt Nieko C NC Menke Frank F Kirkendall Eric E Butler Dawn D Duggan Thomas J TJ Cortezzo DonnaMaria E DE Kiger Sam S Dietrich Tom T Spencer Paul P Keefer Rob R Setchell Kenneth D R KDR Zhao Junfang J Euteneuer Joshua C JC Mizuno Tomoyuki T Dufendach Kevin R KR
Clinical pharmacology and therapeutics 20191211 1
Morphine is the opioid most commonly used for neonatal pain management. In intravenous form, it is administered as continuous infusions and intermittent injections, mostly based on empirically established protocols. Inadequate pain control in neonates can cause long-term adverse consequences; however, providing appropriate individualized morphine dosing is particularly challenging due to the interplay of rapid natural physiological changes and multiple life-sustaining procedures in patients who ...[more]