Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC7379871 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in oncology 20200717
Epidermal growth factor receptor (EGFR) mutations are common in non-small cell lung cancers, but rare in small cell lung cancers (SCLCs). In previous reports, some SCLC patients with EGFR mutations could benefit from EGFR tyrosine kinase inhibitors (TKIs). In this study, we reported a case in which an SCLC patient with EGFR exon 19 deletion (19-Del) mutation did not benefit from EGFR-TKIs. Interestingly, the standard treatment strategies for SCLC also failed to control tumor progression. Moreove ...[more]